Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.82 |
| ▸ | PPARA | Q07869 | 17/20 | 0.82 |
| ▸ | PPARD | Q03181 | 9/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859210 | 0.90 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4694836 | 0.87 | PPARG (0.84) | PPARGPPARAPPARD | |
| SCHEMBL4688275 | 0.86 | PPARG (0.80) | PPARGPPARAPPARD | |
| SCHEMBL5138740 | 0.86 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL4692584 | 0.84 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL4688254 | 0.83 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL4691387 | 0.82 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL4689959 | 0.79 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL4689096 | 0.79 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4692901 | 0.78 | PPARG (0.68) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | disclosed |