Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.82 |
| ▸ | PPARA | Q07869 | 16/20 | 0.70 |
| ▸ | PPARD | Q03181 | 8/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785200 | 0.89 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2805324 | 0.89 | PPARG (0.84) | PPARGPPARAPPARD | |
| SCHEMBL4689724 | 0.86 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL2810318 | 0.82 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4689579 | 0.82 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4689934 | 0.81 | PPARG (0.85) | PPARGPPARAPPARD | |
| SCHEMBL2811302 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL14288217 | 0.81 | PPARG (0.82) | PPARGPPARAPPARD | |
| SCHEMBL4692541 | 0.81 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL2810217 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | claimed |
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | disclosed |