⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12613762 | 0.98 | — | — | |
| Benzene SCHEMBL27551913 | 0.98 | — | — | |
| Formaldehyde SCHEMBL27781384 | 0.96 | — | — | |
| SCHEMBL670160 | 0.80 | — | — | |
| Oxalic Acid SCHEMBL28284567 | 0.70 | — | — | |
| SCHEMBL27272941 | 0.62 | — | — | |
| SCHEMBL28809329 | 0.62 | — | — | |
| SCHEMBL27420253 | 0.61 | — | — | |
| SCHEMBL1426598 | 0.60 | — | — | |
| SCHEMBL7853628 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743483-B | NADPH oxidase 4 inhibitors | 埃科特莱茵药品有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-107743483-A | NADPH oxidase 4 inhibitors | 埃科特莱茵药品有限公司 | 2018-02-27 | — | — | CN | claimed |
| EP-3246328-A1 | QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2017-11-22 | — | — | EP | claimed |
| CN-105198904-B | The preparation method of lavo-ofloxacin and Ofloxacin | 上虞京新药业有限公司 | 2017-08-15 | — | — | CN | claimed |
| CN-105198904-A | Preparing method for levofloxacin and ofloxacin | SHANGYU JINGXINN PHARMACEUTICAL CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104910177-A | Aminomethyl triazole-substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and application thereof | UNIV HENAN | 2015-09-16 | — | — | CN | claimed |
| CN-104817572-A | Chiral aminomethyl aminomethyl triazole substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and applications thereof | UNIV HENAN | 2015-08-05 | — | — | CN | claimed |
| CN-103764652-A | Tricyclic pyrazole sulfonamide compounds and methods of making and using same | ZAFGEN CORP | 2014-04-30 | — | — | CN | claimed |
| CN-101184487-B | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA NV | 2010-11-03 | — | — | CN | claimed |
| CN-101379044-A | Heterobicyclic sulfonamide derivatives for the treatment of diabetes | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | claimed |
| CN-101035784-A | New bicyclic antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-12 | — | — | CN | claimed |
| CN-1332962-C | Method of synthesizing methanesulfonic acid parzhushaxing intermedinte | WUHAN RENFU PHARMACEUTICAL CO (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-1780823-A | Heteroaromatic pentacyclic compound and medicinal use thereof | JAPAN TOBACCO INC (JP) | 2006-05-31 | — | — | CN | claimed |
| CN-1724537-A | Method of synthesizing methanesulfonic acid parzhushaxing intermedinte | WUHAN RENFU PHARMACEUTICAL CO (CN) | 2006-01-25 | — | — | CN | claimed |
| CN-1078236-A | Pyridine a pair of horses going side by side (1,2,3)-1, the catalysis synthesizing technology of 4-benzene a pair of horses going side by side oxazine derivative | ZHENGZHOU POLYTECHNICAL COLLEG (CN) | 1993-11-10 | — | — | CN | claimed |
| CN-113226310-B | 15-PGDH inhibitors | 杏林制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| CN-116969971-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-1079745-A | New 9-fluoro-7-oxo-7H-pyrido [1,2,3-d, e] [1,4] benzoxazine-6-carboxylic acids and ester thereof | BAYER AG (DE) | 1993-12-22 | — | — | CN | disclosed |
| CN-1078236-A | Pyridine a pair of horses going side by side (1,2,3)-1, the catalysis synthesizing technology of 4-benzene a pair of horses going side by side oxazine derivative | ZHENGZHOU POLYTECHNICAL COLLEG (CN) | 1993-11-10 | — | — | CN | disclosed |
| CN-1068115-A | 7-iso-dihydro-indole-group-quinolone and-1,4 dihydros-1,8 naphthyridine-4-keto carboxylic acid derivatives | BAYER AG (DE) | 1993-01-20 | — | — | CN | disclosed |