⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004144 | 0.78 | — | — | |
| SCHEMBL1332091 | 0.78 | — | — | |
| SCHEMBL35161 | 0.78 | — | — | |
| SCHEMBL9818733 | 0.78 | — | — | |
| SCHEMBL15216106 | 0.76 | TSHR (0.50) | — | |
| Fluoride SCHEMBL28061709 | 0.74 | — | — | |
| Water SCHEMBL27537799 | 0.74 | — | — | |
| SCHEMBL29506885 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27605334 | 0.74 | — | — | |
| SCHEMBL28894528 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777051-B | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117777051-A | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-8501785-B2 | Salts of benzimidazolyl pyridyl ethers and formulations thereof | NOVARTIS AG (CH) | 2013-08-06 | — | — | US | disclosed |
| US-20120308651-A1 | SALTS OF BENZIMIDAZOLYL PYRIDYL ETHERS AND FORMULATIONS THEREOF | NOVARTIS AG | 2012-12-06 | — | — | US | disclosed |
| EP-1966222-A2 | PYRAZOLOTHIAZOLE PROTEIN KINASE MODULATORS | SGX Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | SGX PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| WO-2007059341-A2 | PYRAZOLOTHIAZOLE PROTEIN KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |