Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695537 | 1.00 | KCNA5 (0.34) | KCNA5KDM4ENPC1RAB9APOLB | |
| SCHEMBL4695543 | 1.00 | KCNA5 (0.34) | KCNA5KDM4ENPC1RAB9APOLB | |
| SCHEMBL5185334 | 0.94 | KCNA5 (0.33) | KCNA5NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL22030701 | 0.93 | KCNA5 (0.33) | KCNA5NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL4130799 | 0.92 | POLB (0.35) | KCNA5NPC1RAB9APOLBLMNA | |
| SCHEMBL4130795 | 0.92 | POLB (0.35) | KCNA5NPC1RAB9APOLBLMNA | |
| SCHEMBL4155718 | 0.91 | SMN1; SMN2 (0.39) | KDM4ENPC1RAB9APOLBCYP3A4 | |
| SCHEMBL4155713 | 0.91 | SMN1; SMN2 (0.39) | KDM4ENPC1RAB9APOLBCYP3A4 | |
| SCHEMBL22030700 | 0.91 | KCNA5 (0.32) | KCNA5NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL22031083 | 0.90 | PLA2G10 (0.37) | KCNA5KDM4ENPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |