Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.61 |
| ▸ | PPARG | P37231 | 19/20 | 0.61 |
| ▸ | PPARD | Q03181 | 11/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805399 | 0.89 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL4692465 | 0.86 | PPARG (0.61) | PPARAPPARGPPARD | |
| SCHEMBL4696094 | 0.85 | PPARA (0.62) | PPARAPPARGPPARD | |
| SCHEMBL4695140 | 0.80 | PPARG (0.68) | PPARAPPARGPPARD | |
| SCHEMBL4692287 | 0.80 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL4689583 | 0.79 | PPARG (0.67) | PPARAPPARGPPARD | |
| SCHEMBL4750583 | 0.79 | PPARG (0.67) | PPARAPPARGPPARD | |
| SCHEMBL4692539 | 0.78 | PPARG (0.66) | PPARAPPARGPPARD | |
| SCHEMBL4694582 | 0.77 | PPARG (0.67) | PPARAPPARGPPARD | |
| SCHEMBL4691567 | 0.77 | PPARG (0.81) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | PPARD, PPARA, PPARG | PPARA 2/4885PPARG 3/4885PPARD 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.