Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.65 |
| ▸ | FNTB | P49356 | 11/20 | 0.65 |
| ▸ | HRAS | P01112 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696711 | 0.97 | FNTA (0.64) | FNTAFNTBHRASKRAS | |
| SCHEMBL4694699 | 0.96 | FNTA (0.63) | FNTAFNTBHRASKRAS | |
| SCHEMBL4694574 | 0.96 | FNTA (0.63) | FNTAFNTBHRASKRAS | |
| SCHEMBL4697627 | 0.95 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL4693727 | 0.90 | FNTA (0.64) | FNTAFNTBHRASKRAS | |
| SCHEMBL14290012 | 0.84 | FNTA (0.68) | FNTAFNTBHRASKRAS | |
| SCHEMBL14289913 | 0.84 | FNTA (0.65) | FNTAFNTB | |
| SCHEMBL4693539 | 0.84 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL4697795 | 0.84 | FNTA (0.63) | FNTAFNTB | |
| SCHEMBL4697563 | 0.82 | FNTA (0.53) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318994-B1 | SUBSTITUTED IMIDAZOLES AS DUAL HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS | SCHERING CORP (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1318994-B1 | SUBSTITUTED IMIDAZOLES AS DUAL HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS | SCHERING CORP (US) | 2008-02-27 | — | — | EP | disclosed |
| US-6506756-B2 | For treatment of allergies, inflammatory and central nervous system related diseases | SCHERING CORPORATION | 2003-01-14 | — | — | US | disclosed |