Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600 | 1.00 | TDP1 (0.41) | TDP1CA1CA2CA9CA12 | |
| SCHEMBL3158336 | 1.00 | TDP1 (0.41) | TDP1CA1CA2CA9CA12 | |
| SCHEMBL28159040 | 0.96 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Benzene SCHEMBL28239903 | 0.96 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 | |
| Benzene SCHEMBL28943358 | 0.96 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 | |
| SCHEMBL28047489 | 0.96 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 | |
| SCHEMBL49343 | 0.96 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 | |
| Benzene SCHEMBL4445625 | 0.96 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL28731681 | 0.93 | CA1 (0.37) | TDP1CA1CA2CA9CA12 | |
| Ethane SCHEMBL4318566 | 0.93 | TSHR (0.37) | TDP1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120349290-B | Resist, preparation method, composition, adhesive layer and pattern forming method | 南开大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-117940408-A | Acridine compounds | 国立大学法人大阪大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-110959010-B | Metal complex | UDC爱尔兰有限公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2023110970-A1 | MACROCYCLIC BTK INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |
| CN-107109221-B | Bimesogenic compounds and mesogenic media | 默克专利股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-108147972-A | A kind of preparation method of Wei Patawei intermediates and the like | 成都西岭源药业有限公司 | 2018-06-12 | — | — | CN | disclosed |
| EP-1963273-A2 | SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007075783-A2 | SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITOR | WYETH (US) | 2007-07-05 | — | — | WO | disclosed |
| US-6509337-B1 | A method of treating a mammalian disease condition mediated by metalloproteinase activity which comprises administering to a mammal in need thereof a therapeutically effective amount of a compound as defined in claim 1 or a pharmaceutically | PFIZER INC. | 2003-01-21 | — | — | US | disclosed |
| US-6169183-B1 | REACTING 2,3-DIHALOPYRIDINE WITH CARBON MONOXIDE AND ALKANOL IN PRESENCE OF WEAK BASE AND COMPLEX OF PALLADIUM WITH SPECIFIED BIS(DIPHENYLPHOSPHINE), WHEREIN REACTION IS STOPPED AS SOON AS MAXIMUM CONCENTRATION OF ESTER IS ACHIEVED | LONZA, LTD. (CH) | 2001-01-02 | — | — | US | disclosed |
| US-6162921-A | Process for preparing pyridinecarboxylic esters | LONZA, LTD (CH) | 2000-12-19 | — | — | US | disclosed |
| US-6022973-A | Process for preparing pyridinecarboxylic esters | LONZA LTD. (CH) | 2000-02-08 | — | — | US | disclosed |
| US-5925765-A | Process for preparing pyridinecarboxylic esters | LONZA AG (CH) | 1999-07-20 | — | — | US | disclosed |