Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914978 | 1.00 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL914977 | 1.00 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915926 | 0.89 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL916331 | 0.89 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915221 | 0.89 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL916333 | 0.89 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915961 | 0.88 | KMT2A (0.48) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915962 | 0.88 | KMT2A (0.48) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915874 | 0.88 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1POLBPLG | |
| SCHEMBL915989 | 0.88 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1POLBPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |