Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3886218 | 0.99 | AURKA (0.98) | AURKA | |
| SCHEMBL4693855 | 0.93 | AURKA (0.86) | AURKA | |
| SCHEMBL3885418 | 0.89 | AURKA (1.00) | AURKA | |
| SCHEMBL3887853 | 0.89 | AURKA (0.81) | AURKA | |
| SCHEMBL3880426 | 0.87 | AURKA (0.85) | AURKA | |
| SCHEMBL3881035 | 0.87 | AURKA (0.79) | AURKA | |
| SCHEMBL3881075 | 0.87 | AURKA (0.85) | AURKA | |
| SCHEMBL3881629 | 0.87 | AURKA (1.00) | AURKA | |
| SCHEMBL3883428 | 0.87 | AURKA (0.77) | AURKA | |
| SCHEMBL3880769 | 0.87 | AURKA (0.80) | AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534716-B1 | HETEROBICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PFIZER ITALIA SRL (IT) | 2008-04-23 | — | — | EP | claimed |