Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 12/20 | 0.50 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.50 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.50 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.50 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.42 |
| ▸ | ADCYAP1R1 | P41586 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46632 | 0.89 | SLC34A2 (0.56) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL47000 | 0.87 | SLC34A2 (0.43) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL15421167 | 0.87 | SLC34A2 (0.43) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL40258 | 0.87 | SLC34A2 (0.54) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL46609 | 0.87 | SLC34A2 (0.54) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL40259 | 0.87 | SLC34A2 (0.54) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL15420752 | 0.83 | SLC34A2 (0.51) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL15420751 | 0.83 | SLC34A2 (0.51) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL15421293 | 0.83 | SLC34A2 (0.51) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 | |
| SCHEMBL274461 | 0.83 | SLC34A2 (0.57) | SLC34A2SLC34A1SLC34A3SLC20A1HSPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |