Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.56 |
| ▸ | TACR1 | P25103 | 8/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471731 | 0.92 | CNR2 (0.58) | CNR2TACR1TACR2KDM4EMEN1 | |
| SCHEMBL4483088 | 0.88 | CNR2 (0.60) | CNR2TACR1TACR2KDM4EALDH1A1 | |
| SCHEMBL4479887 | 0.86 | CNR2 (0.58) | CNR2TACR1TACR2KDM4EMEN1 | |
| SCHEMBL4488066 | 0.85 | CNR2 (0.57) | CNR2TACR1TACR2KDM4EMEN1 | |
| SCHEMBL4480824 | 0.85 | CNR2 (0.59) | CNR2TACR1TACR2KDM4EALDH1A1 | |
| SCHEMBL4472304 | 0.84 | CNR2 (0.58) | CNR2TACR1TACR2KDM4EALDH1A1 | |
| SCHEMBL4469512 | 0.83 | CNR2 (0.56) | CNR2TACR1TACR2KDM4EMAPT | |
| SCHEMBL4468418 | 0.81 | CNR2 (0.64) | CNR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4489036 | 0.81 | CNR2 (0.64) | CNR2TACR1KDM4EALDH1A1MEN1 | |
| SCHEMBL4476107 | 0.80 | CNR2 (0.66) | CNR2TACR1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |