Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752653 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3744685 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3752647 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL4697391 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3744695 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL4697389 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3744690 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3752644 | 1.00 | DPP4 (0.71) | DPP4GAANOTUMALDH1A1 | |
| SCHEMBL3745719 | 0.89 | DPP4 (0.59) | DPP4GAAALDH1A1 | |
| SCHEMBL3747790 | 0.89 | DPP4 (0.59) | DPP4GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919854-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007027651-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | claimed |
| EP-1919854-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007027651-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |