Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999829 | 0.94 | SLC34A2 (0.70) | SLC34A2ROCK2ROCK1GPR52MAPK14 | |
| SCHEMBL46730 | 0.88 | SLC34A2 (0.70) | SLC34A2ROCK2ROCK1GPR52MAPK14 | |
| SCHEMBL46719 | 0.87 | SLC34A2 (0.72) | SLC34A2ROCK2ROCK1GPR52MAPK14 | |
| SCHEMBL40027 | 0.86 | SLC34A2 (0.69) | SLC34A2ROCK2ROCK1MAPK14HTT | |
| SCHEMBL46671 | 0.85 | SLC34A2 (0.67) | SLC34A2ROCK2ROCK1MAPK14HTT | |
| SCHEMBL46448 | 0.85 | SLC34A2 (0.69) | SLC34A2ROCK2ROCK1MAPK14HTT | |
| SCHEMBL40087 | 0.85 | SLC34A2 (0.61) | SLC34A2ROCK2ROCK1GPR52MAPK14 | |
| SCHEMBL46672 | 0.84 | SLC34A2 (0.68) | SLC34A2ROCK2ROCK1MAPK14MLYCD | |
| SCHEMBL46450 | 0.84 | SLC34A2 (0.79) | SLC34A2ROCK2ROCK1GPR52MAPK14 | |
| SCHEMBL39668 | 0.83 | SLC34A2 (0.64) | SLC34A2ROCK2ROCK1GPR52MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |