SCHEMBL469744

SCHEMBL469744

COCCOc1ccc(Cc2cc(C3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)sc2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457169 1.00 SLC5A2 (1.00) SLC5A2
SCHEMBL456825 0.91 SLC5A2 (1.00) SLC5A2
SCHEMBL456805 0.91 SLC5A2 (1.00) SLC5A2
SCHEMBL457054 0.89 SLC5A2 (1.00) SLC5A2
SCHEMBL15086109 0.89 SLC5A2 (1.00) SLC5A2
SCHEMBL460890 0.89 SLC5A2 (1.00) SLC5A2
SCHEMBL454596 0.85 SLC5A2 (1.00) SLC5A2
SCHEMBL456654 0.85 SLC5A2 (1.00) SLC5A2
SCHEMBL462116 0.85 SLC5A2 (1.00) SLC5A2
SCHEMBL455414 0.84 SLC5A2 (1.00) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012033390-A2 NOVEL THIOPHENE DERIVATIVE AS SGLT2 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME GREEN CROSS CORPORATION (KR) 2012-03-15 WO disclosed