Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 4/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | FGF1 | P05230 | 3/20 | 0.32 |
| ▸ | FGF2 | P09038 | 3/20 | 0.32 |
| ▸ | VEGFA | P15692 | 3/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255412 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL12556188 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL14392184 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL15883987 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL18483745 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL10134736 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL12000785 | 0.98 | SMN1; SMN2 (0.42) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL15255431 | 0.91 | SSTR1 (0.42) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL12000748 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2GJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL12580875 | 0.87 | GBA1 (0.33) | SMN1; SMN2GJB2GBA1FGF1FGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012165914-A2 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORPORATION (KR) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012033390-A2 | NOVEL THIOPHENE DERIVATIVE AS SGLT2 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2012-03-15 | — | — | WO | disclosed |