Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23692394 | 0.90 | NTRK1 (0.39) | NTRK1TGFBR1 | |
| SCHEMBL21625418 | 0.89 | NTRK1 (0.38) | NTRK1TGFBR1 | |
| SCHEMBL30100803 | 0.89 | NTRK1 (0.38) | NTRK1TGFBR1 | |
| SCHEMBL30100804 | 0.89 | NTRK1 (0.38) | NTRK1TGFBR1 | |
| SCHEMBL431754 | 0.88 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL464572 | 0.88 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL464567 | 0.88 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL431616 | 0.88 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL433722 | 0.88 | NTRK1 (0.40) | NTRK1 | |
| SCHEMBL431961 | 0.86 | NTRK1 (0.42) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034091-A1 | IMIDAZO [1, 2] PYRIDAZIN COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS | IRM LLC (BM) | 2012-03-15 | — | — | WO | disclosed |