Cyclopentane

Cyclopentane

SCHEMBL4697690

C1CCCC1.Cn1ncc(Br)c1-c1cc(NC(=O)O)ccc1OCCN1CCOCC1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 20/20 0.77
HTR2C P28335 18/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1166607 0.88 HTR2A (0.73) HTR2AHTR2C
SCHEMBL1165604 0.88 HTR2A (0.73) HTR2AHTR2C
SCHEMBL1165681 0.88 HTR2A (0.75) HTR2AHTR2C
SCHEMBL1165586 0.87 HTR2A (1.00) HTR2AHTR2C
SCHEMBL1165629 0.87 HTR2A (0.74) HTR2AHTR2C
SCHEMBL1166295 0.87 HTR2A (0.73) HTR2AHTR2C
SCHEMBL1165609 0.87 HTR2A (0.71) HTR2AHTR2C
SCHEMBL1166053 0.86 HTR2A (0.73) HTR2AHTR2C
SCHEMBL1862027 0.86 HTR2A (0.94) HTR2AHTR2C
SCHEMBL1166272 0.86 HTR2A (0.74) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833799-B1 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT-2a SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2008-09-10 EP claimed