Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.36 |
| ▸ | PDE4A | P27815 | 9/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907503 | 0.69 | — | — | |
| SCHEMBL874456 | 0.68 | PDE4A (0.36) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL7987198 | 0.64 | POLB (0.30) | — | |
| SCHEMBL3795340 | 0.59 | — | — | |
| SCHEMBL5084709 | 0.59 | CA12 (0.54) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL24806043 | 0.57 | PDE4A (0.53) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1071370 | 0.57 | MAPT (0.53) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL2909706 | 0.57 | PDE4A (0.51) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL12303123 | 0.56 | SLC6A2 (0.63) | PDE4BPDE4A | |
| SCHEMBL3148517 | 0.56 | MAPT (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940810-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | Ranbaxy Laboratories Limited (IN) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007046022-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |