Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.35 |
| ▸ | ITGAV | P06756 | 8/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701526 | 0.94 | GAA (0.40) | HTR5AGAAITGB3ITGAVITGB5 | |
| SCHEMBL4700500 | 0.92 | POLB (0.43) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL6122200 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL20530282 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL6127110 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL4698443 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL17009347 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL6127212 | 0.92 | POLB (0.46) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL7900077 | 0.88 | HPGD (0.44) | POLBHPGDTRPM8GAAITGB3 | |
| SCHEMBL4698454 | 0.88 | POLB (0.42) | POLBHPGDTRPM8GAAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |