Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697841 | 1.00 | KCNA5 (0.32) | KCNA5L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20557547 | 0.93 | KCNA5 (0.33) | KCNA5POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4130799 | 0.91 | POLB (0.35) | KCNA5L3MBTL1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4130795 | 0.91 | POLB (0.35) | KCNA5L3MBTL1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL5253690 | 0.89 | KCNA5 (0.35) | KCNA5MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL20557553 | 0.88 | KCNA5 (0.32) | KCNA5POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21980501 | 0.87 | GAA (0.31) | GAA | |
| SCHEMBL20557817 | 0.87 | KCNA5 (0.36) | KCNA5SMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL2066952 | 0.87 | KCNA5 (0.36) | KCNA5SMN1; SMN2POLBCYP3A4CYP2C9 | |
| SCHEMBL4695499 | 0.87 | MEN1 (0.31) | KCNA5SMN1; SMN2MEN1KMT2APFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |