SCHEMBL4697913

SCHEMBL4697913

OC1=CNC=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28488779 0.97
Hydrochloric Acid SCHEMBL27651142 0.97
Hydrochloric Acid SCHEMBL28297432 0.91
Benzene SCHEMBL28096982 0.69
SCHEMBL5653901 0.67
SCHEMBL27331102 0.67
SCHEMBL27676732 0.67
SCHEMBL28096555 0.67
SCHEMBL30507521 0.67
SCHEMBL28229477 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094234-B Synthesis method of 6-phenyl-2, 3,4, 7-tetrahydro-1H-3-azepine derivative 山东理工大学 2023-07-07 CN claimed
CN-112094234-A Synthetic method of 6-phenyl-2, 3,4, 7-tetrahydro-1H-3-azepinol derivative 山东理工大学 2020-12-18 CN claimed
US-4241060-A FOR SENSITIZING HYPOXIC CELLS TO RADIATION; ANTIPROTOZAL AGENTS HOFFMANN-LA ROCHE INC. (US) 1980-12-23 US claimed
CN-112521364-B Galanthamine intermediate compound V 鲁南制药集团股份有限公司 2023-09-05 CN disclosed
CN-112521395-B Preparation method of galanthamine 鲁南制药集团股份有限公司 2023-09-05 CN disclosed
CN-112094234-B Synthesis method of 6-phenyl-2, 3,4, 7-tetrahydro-1H-3-azepine derivative 山东理工大学 2023-07-07 CN disclosed
CN-112094234-B Synthesis method of 6-phenyl-2, 3,4, 7-tetrahydro-1H-3-azepine derivative 山东理工大学 2023-07-07 CN disclosed
CN-110003214-B Substituted pyrazolo [1,5-a ] pyrimidine compounds as TRK kinase inhibitors 阵列生物制药公司 2021-12-21 CN disclosed
CN-112094234-A Synthetic method of 6-phenyl-2, 3,4, 7-tetrahydro-1H-3-azepinol derivative 山东理工大学 2020-12-18 CN disclosed
WO-2020230718-A1 GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYHEXANEDIOIC ACID, (E)-HEX-2-ENEDIOIC ACID AND/OR HEXANEDIOIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICALS 東レ株式会社 2020-11-19 WO disclosed
CN-110214136-A Pyrazole derivatives as MALT1 inhibitor 詹森药业有限公司 2019-09-06 CN disclosed
WO-2000015610-A1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2000-03-23 WO disclosed
CN-1044814-C Process for stabilizing trivalent phosphorus compounds with amines CIBA SC HOLDING AG (CH) 1999-08-25 CN disclosed
US-5708168-A FOR TREATING OR PREVENTING NEURONAL LOSS STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1998-01-13 US disclosed
US-5674866-A Antiallergic imidazoazepines JANSSEN PHARMACEUTICA N.V. (BE) 1997-10-07 US disclosed
WO-1996015112-A1 AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION ACEA PHARMACEUTICALS, INC. (US) 1996-05-23 WO disclosed
US-5476933-A Condensation, ring expansion STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) 1995-12-19 US disclosed
EP-0350051-A1 Thaz derivatives for enhancemet of cerebral function Bristol-Myers Squibb Company (US) 1990-01-10 EP disclosed
US-4859666-A THAZ derivatives for enhancement of cerebral function BRISTOL-MYERS COMPANY (US) 1989-08-22 US disclosed
CN-85101404-A The production process of cephalosporins derivatives 1987-01-17 CN disclosed