Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 19/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173175 | 0.92 | BDKRB1 (0.61) | BDKRB1 | |
| SCHEMBL4174733 | 0.85 | BDKRB1 (0.69) | BDKRB1LMNAKMT2A | |
| SCHEMBL4172026 | 0.83 | BDKRB1 (0.71) | BDKRB1 | |
| SCHEMBL13499183 | 0.83 | BDKRB1 (0.66) | BDKRB1 | |
| SCHEMBL4162090 | 0.83 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4176920 | 0.83 | BDKRB1 (0.69) | BDKRB1LMNAKMT2A | |
| SCHEMBL3535672 | 0.82 | BDKRB1 (0.65) | BDKRB1 | |
| SCHEMBL3535670 | 0.82 | BDKRB1 (0.65) | BDKRB1 | |
| SCHEMBL4167172 | 0.81 | BDKRB1 (0.69) | BDKRB1 | |
| SCHEMBL3534905 | 0.80 | BDKRB1 (0.61) | BDKRB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963285-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067629-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2007-06-14 | — | — | WO | disclosed |