Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PHGDH | O43175 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698001 | 1.00 | HTT (0.48) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL13673637 | 0.89 | HTT (0.49) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL13673635 | 0.89 | HTT (0.49) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL915537 | 0.85 | MAPT (0.47) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL13673500 | 0.85 | HTT (0.56) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL13673499 | 0.85 | HTT (0.56) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL4701661 | 0.84 | KMT2A (0.54) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL4701658 | 0.84 | KMT2A (0.54) | HTTKDM4EMAPTALDH1A1PHGDH | |
| SCHEMBL4701023 | 0.83 | MEN1 (0.59) | HTTKDM4EMAPTALDH1A1POLB | |
| SCHEMBL4701025 | 0.83 | MEN1 (0.59) | HTTKDM4EMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |