Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 20/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | GHSR | Q92847 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127648 | 1.00 | MLNR (0.74) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4698259 | 1.00 | MLNR (0.74) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL5121269 | 0.88 | MLNR (0.73) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4697045 | 0.88 | MLNR (0.73) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4697087 | 0.85 | MLNR (1.00) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4699580 | 0.85 | MLNR (1.00) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4754350 | 0.84 | MLNR (0.92) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4696839 | 0.83 | MLNR (1.00) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4700720 | 0.83 | MLNR (1.00) | MLNRCYP3A4CYP2D6GHSR | |
| Hydrochloric Acid SCHEMBL5128213 | 0.82 | MLNR (0.98) | MLNRCYP3A4CYP2D6GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902022-A1 | PIPERAZINE HETEROARYL DERIVATES AS GPR38 AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-03-26 | — | — | EP | claimed |
| WO-2007007018-A1 | PIPERAZINE HETEROARYL DERIVATES AS GPR38 AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-01-18 | — | — | WO | claimed |
| EP-1902022-A1 | PIPERAZINE HETEROARYL DERIVATES AS GPR38 AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007018-A1 | PIPERAZINE HETEROARYL DERIVATES AS GPR38 AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-01-18 | — | — | WO | disclosed |