⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035778 | 0.64 | PLG (0.38) | — | |
| SCHEMBL19122656 | 0.61 | — | — | |
| SCHEMBL20457669 | 0.57 | — | — | |
| SCHEMBL375904 | 0.55 | — | — | |
| SCHEMBL29465177 | 0.54 | — | — | |
| SCHEMBL29465156 | 0.54 | — | — | |
| SCHEMBL28027264 | 0.52 | — | — | |
| SCHEMBL7948348 | 0.51 | — | — | |
| SCHEMBL29465180 | 0.50 | — | — | |
| SCHEMBL13602035 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001885-A2 | OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES | Abbott Laboratories (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007100990-A2 | OCTAHYDRO-PYRROLO[3,4-B] PYRROLE DERIVATIVES AND THEIR USE AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-09-07 | — | — | WO | claimed |
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| CN-114573604-B | Quinolone-based compound, preparation method thereof, pharmaceutical composition containing quinolone-based compound and application of quinolone-based compound | 中国科学院上海药物研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-106928200-A | For the pyrrolotriazine derivatives for the treatment of cancer | 湖南福沃药业有限公司 | 2017-07-07 | — | — | CN | disclosed |