Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CTSD | P07339 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364846 | 1.00 | MLNR (0.63) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL8393089 | 1.00 | MLNR (0.63) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL19605372 | 1.00 | MLNR (0.63) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL13915948 | 0.89 | MLNR (0.61) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL3027706 | 0.87 | MLNR (0.60) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL21207977 | 0.87 | MLNR (0.62) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL13915939 | 0.85 | MLNR (0.57) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL14137602 | 0.85 | MLNR (0.52) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL3029709 | 0.85 | MLNR (0.60) | MLNRABCB11LMNACTSDCYP3A4 | |
| SCHEMBL1601587 | 0.85 | MLNR (0.63) | MLNRABCB11LMNACTSDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032389-A2 | PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE FOSAMPRENAVIR CALCIUM AND ITS INTERMEDIATES | LUPIN LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |