Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972713 | 0.85 | ESR1 (0.46) | TTRALOX5PTGS1PTGS2ESR1 | |
| SCHEMBL2050141 | 0.83 | ESR1 (0.57) | CYP1A2CYP2C9CYP2C19ESR1ESR2 | |
| SCHEMBL674118 | 0.81 | ESR1 (0.50) | CYP1A2CYP2C9CYP2C19ALOX5PTGS1 | |
| Ethane SCHEMBL28242861 | 0.80 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19CYP19A1SLC6A2 | |
| SCHEMBL126749 | 0.80 | CYP2C9 (0.58) | CYP1A2CYP2C9CYP2C19CYP19A1SLC6A2 | |
| SCHEMBL2031129 | 0.80 | SLC6A2 (0.44) | CYP1A2CYP2C9CYP2C19TTRALOX5 | |
| Phenol SCHEMBL28598393 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19PTGS1PTGS2 | |
| SCHEMBL30797203 | 0.78 | CYP2C9 (0.56) | CYP1A2CYP2C9CYP2C19CYP19A1SLC6A2 | |
| SCHEMBL10556172 | 0.78 | CYP2C9 (0.56) | CYP1A2CYP2C9CYP2C19CYP19A1SLC6A2 | |
| Water SCHEMBL28108007 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19CYP19A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969030-A2 | POLY (ARYLENE ETHER) COPOLYMER | GENERAL ELECTRIC COMPANY (US) | 2008-09-17 | — | — | EP | claimed |
| WO-2007067669-A2 | POLY (ARYLENE ETHER) COPOLYMER | GENERAL ELECTRIC COMPANY (US) | 2007-06-14 | — | — | WO | claimed |