Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403915 | 0.94 | DPP4 (0.49) | DPP4DPP7DPP9CYP2D6DPP8 | |
| SCHEMBL4402210 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP9CYP2D6DPP8 | |
| SCHEMBL4396792 | 0.78 | DPP4 (0.57) | DPP4DPP7DPP9CYP2D6DPP8 | |
| SCHEMBL4399262 | 0.78 | DPP4 (0.60) | DPP4DPP7DPP9DPP8CYP3A4 | |
| SCHEMBL4406694 | 0.78 | DPP4 (0.60) | DPP4DPP7DPP9DPP8CYP3A4 | |
| SCHEMBL4403549 | 0.78 | DPP4 (0.50) | DPP4DPP7DPP9CYP2D6DPP8 | |
| SCHEMBL4551513 | 0.78 | DPP4 (0.61) | DPP4DPP7DPP9CYP3A4 | |
| SCHEMBL4399272 | 0.78 | DPP4 (0.61) | DPP4DPP7DPP9CYP3A4 | |
| SCHEMBL4398889 | 0.76 | DPP4 (0.64) | DPP4DPP7DPP9DPP8CYP3A4 | |
| SCHEMBL4412229 | 0.75 | DPP4 (0.51) | DPP4DPP7DPP9CYP2D6DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | claimed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | claimed |
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | disclosed |