SCHEMBL4698587

SCHEMBL4698587

CCC(=O)OC(CC)OC(=O)C(N)C1CCC(C(=O)O)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.34
ENPEP Q07075 1/20 0.34
PLG P00747 1/20 0.33
PLAT P00750 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915721 1.00 ANPEP (0.34) ANPEPENPEPPLGPLATLMNA
SCHEMBL4700077 0.91 ANPEP (0.32) ANPEPENPEPPLGPLATLMNA
SCHEMBL914979 0.91 ANPEP (0.32) ANPEPENPEPPLGPLATLMNA
SCHEMBL3256826 0.90 ANPEP (0.35) ANPEPENPEPPLGPLATLMNA
SCHEMBL916188 0.90 ANPEP (0.35) ANPEPENPEPPLGPLATLMNA
SCHEMBL915023 0.89 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL4698912 0.89 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL915947 0.86 ANPEP (0.36) ANPEPENPEPPLGPLATLMNA
SCHEMBL8220093 0.85 KMT2A (0.32) ANPEPENPEPPLGPLATLMNA
SCHEMBL916653 0.85 KMT2A (0.32) ANPEPENPEPPLGPLATLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101253148-B Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use XENOPORT INC 2013-01-02 CN claimed
CN-101253148-A Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use XENOPORT INC (US) 2008-08-27 CN claimed
CN-101253148-B Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use XENOPORT INC 2013-01-02 CN disclosed
WO-2011028234-A1 USES OF ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID XENOPORT, INC. (US) 2011-03-10 WO disclosed
CN-101253148-A Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use XENOPORT INC (US) 2008-08-27 CN disclosed
EP-1919859-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE Xenoport, Inc. (US) 2008-05-14 EP disclosed
WO-2007002013-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2007-01-04 WO disclosed