SCHEMBL4698708

SCHEMBL4698708

CCCCCCCCC[Si](C)(C)O[Si](C)(C)O[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4708830 1.00 TSHR (0.31) TSHRTHRB
SCHEMBL9146718 0.96
SCHEMBL92394 0.92
SCHEMBL18031713 0.92
SCHEMBL12909786 0.89
SCHEMBL12245413 0.89
SCHEMBL12873394 0.89
SCHEMBL16140788 0.89
SCHEMBL15281226 0.89
SCHEMBL2454029 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011626-B1 Solid water-in-oil cosmetic emulsion containing a silicone surfactant of alkyl-dimethicone copolyol type and an oily phase including at least one silicone oil and a polyethylene wax OREAL (FR) 2005-06-29 EP claimed
EP-1155676-A2 Composition for make-up or skin-care in a powdery form and containing a particular binder L'OREAL (FR) 2001-11-21 EP claimed
EP-0857481-B1 Use of an organopolysiloxane for the fixing and/or the prolonged release of perfume OREAL (FR) 2001-02-07 EP claimed
EP-1023890-A1 Anhydrous composition, use in cosmetics, in pharmacy or for hygiene L'OREAL (FR) 2000-08-02 EP claimed
EP-1011626-A1 USE OF A SILICONE SURFACTANT OF ALKYL-DIMETHICONE COPOLYOL TYPE FOR PREPARING SOLID WATER-IN-OIL COSMETIC EMULSIONS AND RESULTING SOLID WATER-IN-OIL EMULSIONS L'OREAL (FR) 2000-06-28 EP claimed
WO-1999047111-A1 USE OF A SILICONE SURFACTANT OF ALKYL-DIMETHICONE COPOLYOL TYPE FOR PREPARING SOLID WATER-IN-OIL COSMETIC EMULSIONS AND RESULTING SOLID WATER-IN-OIL EMULSIONS L'OREAL (FR) 1999-09-23 WO claimed
EP-3691604-B1 MATTE LIPSTICK COMPOSITION CHANEL PARFUMS BEAUTE (FR) 2023-09-13 EP disclosed
EP-3930678-A1 SOLID COSMETIC COMPOSITION THAT GLIDES ON AND MELTS AWAY ON APPLICATION Chanel Parfums Beauté (FR) 2022-01-05 EP disclosed
EP-3576713-B1 SOLID WATER-IN-OIL COSMETIC EMULSION CHANEL PARFUMS BEAUTE (FR) 2020-12-09 EP disclosed
EP-3691604-A2 MATTE LIPSTICK COMPOSITION Chanel Parfums Beauté (FR) 2020-08-12 EP disclosed
WO-2019069035-A2 MATTE LIPSTICK COMPOSITION CHANEL PARFUMS BEAUTE (FR) 2019-04-11 WO disclosed
WO-2019069036-A1 SOLID COSMETIC COMPOSITION COMPRISING A WAX AND/OR A PASTE COMPOUND AND AT LEAST ONE ANTI-EXUDATION FILLER CHANEL PARFUMS BEAUTE (FR) 2019-04-11 WO disclosed
WO-2018142076-A1 SOLID WATER-IN-OIL COSMETIC EMULSION CHANEL PARFUMS BEAUTE (FR) 2018-08-09 WO disclosed
EP-0854176-A1 Process for preparing a photochromic compound, the obtained photochromic compound and the cosmetic composition containing it L'OREAL (FR) 1998-07-22 EP disclosed
EP-0847751-A1 Cosmetic compositions containing mineral photochromic compounds L'OREAL (FR) 1998-06-17 EP disclosed
EP-0847752-A1 Without rub off topical composition containing a fluorosilicon compound L'OREAL (FR) 1998-06-17 EP disclosed
EP-0832645-A1 Cosmetic composition comprising a particular copolymer and use of said copolymer in cosmetics L'OREAL (FR) 1998-04-01 EP disclosed
EP-0819418-A1 Composition comprising a hydrophilic compound and the association of a volatile compound and a pasty fatty compound and use of same association L'OREAL (FR) 1998-01-21 EP disclosed
EP-0819428-A2 Composition containing a combination of a volatile compound and a polyvinylpyrrolidone derivative polymer and use thereof L'OREAL (FR) 1998-01-21 EP disclosed
EP-0819419-A1 Composition containing a hydrophilic component, and the combination of a volatile component with a phenylated silicon oil, and use of said combination L'OREAL (FR) 1998-01-21 EP disclosed