Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842860 | 0.95 | ABCB1 (0.56) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL258672 | 0.92 | ABCB1 (0.63) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL588999 | 0.92 | ABCB1 (0.63) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL588614 | 0.92 | ABCB1 (0.63) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL6836270 | 0.92 | ABCB1 (0.63) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL27870163 | 0.92 | ABCB1 (0.63) | PLA2G4BABCB1S1PR1MAPK1LMNA | |
| SCHEMBL11203428 | 0.91 | ABCB1 (0.64) | PLA2G4BABCB1MAPK1LMNAPOLB | |
| SCHEMBL6071806 | 0.83 | MAPT (0.69) | PLA2G4BABCB1S1PR1LMNAPOLB | |
| SCHEMBL8926603 | 0.81 | ABCB1 (0.69) | PLA2G4BABCB1MAPK1LMNAPOLB | |
| SCHEMBL5090793 | 0.81 | TSHR (0.61) | PLA2G4BS1PR1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966145-A2 | FLUORESCENT BRIGHTENERS AND COMPOSITIONS THEREOF, METHODS OF PREPARATION AND USES | The General Electric Company (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007062002-A2 | FLUORESCENT BRIGHTENERS AND COMPOSITIONS THEREOF, METHODS OF PREPARATION AND USES | GENERAL ELECTRIC COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |