Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470289 | 0.96 | TTK (0.77) | TTKCYP3A4 | |
| SCHEMBL15556532 | 0.95 | TTK (0.80) | TTKCYP3A4 | |
| SCHEMBL455615 | 0.90 | TTK (0.68) | TTKCYP3A4 | |
| SCHEMBL459325 | 0.90 | TTK (0.68) | TTKCYP3A4 | |
| SCHEMBL459033 | 0.90 | TTK (0.72) | TTKCYP3A4 | |
| SCHEMBL10279714 | 0.90 | TTK (0.67) | TTKCYP3A4 | |
| SCHEMBL17590102 | 0.89 | TTK (0.66) | TTKCYP3A4 | |
| SCHEMBL455433 | 0.89 | TTK (0.66) | TTKCYP3A4 | |
| SCHEMBL17416392 | 0.89 | TTK (0.68) | TTKCYP3A4 | |
| SCHEMBL12468434 | 0.89 | TTK (0.66) | TTKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | claimed |
| WO-2014020041-A1 | COMBINATIONS FOR THE TREATMENT OF CANCER | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-02-06 | — | — | WO | claimed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |