SCHEMBL4699666

SCHEMBL4699666

Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)CC2(C)C)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173494 1.00 BDKRB1 (0.74) BDKRB1
SCHEMBL4173491 1.00 BDKRB1 (0.74) BDKRB1
SCHEMBL4179978 0.90 BDKRB1 (0.78) BDKRB1
SCHEMBL4179982 0.90 BDKRB1 (0.78) BDKRB1
SCHEMBL4175874 0.89 BDKRB1 (0.81) BDKRB1
SCHEMBL4170032 0.89 BDKRB1 (0.81) BDKRB1
SCHEMBL4170026 0.89 BDKRB1 (0.81) BDKRB1
SCHEMBL4173131 0.89 BDKRB1 (0.81) BDKRB1
SCHEMBL4180773 0.88 BDKRB1 (0.72) BDKRB1
SCHEMBL4699668 0.88 BDKRB1 (0.74) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963285-A1 BRADYKININ 1 RECEPTOR ANTAGONISTS Amgen Inc. (US) 2008-09-03 EP disclosed
WO-2007067629-A1 BRADYKININ 1 RECEPTOR ANTAGONISTS AMGEN INC. (US) 2007-06-14 WO disclosed