Pyridine

Pyridine

SCHEMBL4699770

COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)O)cc21.c1ccncc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPT1A P50416 20/20 0.73
CPT1B Q92523 18/20 0.73
CPT2 P23786 12/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752125 0.94 CPT1A (0.81) CPT1ACPT1BCPT2
SCHEMBL753456 0.85 CPT1A (0.74) CPT1ACPT1BCPT2
SCHEMBL751312 0.85 CPT1A (1.00) CPT1ACPT1BCPT2
SCHEMBL750266 0.85 CPT1A (0.82) CPT1ACPT1BCPT2
SCHEMBL750910 0.84 CPT1A (0.88) CPT1ACPT1BCPT2
SCHEMBL752817 0.84 CPT1A (0.76) CPT1ACPT1BCPT2
SCHEMBL753435 0.83 CPT1A (0.73) CPT1ACPT1BCPT2
SCHEMBL754767 0.83 CPT1A (0.73) CPT1ACPT1BCPT2
SCHEMBL753527 0.81 CPT1A (0.80) CPT1ACPT1BCPT2
SCHEMBL754674 0.80 CPT1A (0.80) CPT1ACPT1BCPT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996563-A1 HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES F.HOFFMANN-LA ROCHE AG (CH) 2008-12-03 EP claimed
WO-2007093507-A1 HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES F. HOFFMANN-LA ROCHE AG (CH) 2007-08-23 WO claimed
EP-1996563-A1 HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES F.HOFFMANN-LA ROCHE AG (CH) 2008-12-03 EP disclosed
WO-2007093507-A1 HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES F. HOFFMANN-LA ROCHE AG (CH) 2007-08-23 WO disclosed