Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.49 |
| ▸ | TTK | P33981 | 6/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458258 | 0.91 | TTK (0.51) | FYNTTKPIM1 | |
| SCHEMBL10279704 | 0.90 | TTK (0.46) | FYNTTKMKNK1 | |
| SCHEMBL456541 | 0.83 | TTK (0.46) | FYNTTKPIM1 | |
| SCHEMBL469994 | 0.81 | FYN (0.47) | FYNTTKMKNK1PIM1 | |
| SCHEMBL459406 | 0.81 | TTK (0.70) | FYNTTK | |
| SCHEMBL470024 | 0.81 | TTK (0.43) | FYNTTKPIM1 | |
| SCHEMBL456226 | 0.81 | TTK (0.41) | FYNTTKPIM1 | |
| SCHEMBL458134 | 0.80 | F2 (0.38) | ASIC1 | |
| SCHEMBL469992 | 0.79 | TTK (0.57) | FYNTTK | |
| SCHEMBL456204 | 0.79 | TTK (0.45) | FYNTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |