Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33260 | 0.92 | CYP1A2 (1.00) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| SCHEMBL13925516 | 0.92 | CYP1A2 (1.00) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| Hydrochloric Acid SCHEMBL2338864 | 0.90 | CYP1A2 (0.94) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| Hydrochloric Acid SCHEMBL22234282 | 0.90 | CYP1A2 (0.94) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| SCHEMBL15223851 | 0.85 | CYP1A2 (0.85) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| Benzene SCHEMBL28312307 | 0.85 | CYP1A2 (0.85) | CYP1A2TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL23277562 | 0.83 | CYP1A2 (0.81) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| SCHEMBL21377151 | 0.83 | CYP1A2 (0.81) | CYP1A2TDP1KDM4ESMN1; SMN2HTR1A | |
| SCHEMBL2616307 | 0.83 | TDP1 (0.81) | CYP1A2TDP1KDM4ESMN1; SMN2HTT | |
| SCHEMBL13779904 | 0.82 | CYP1A2 (0.56) | CYP1A2TDP1HTR1AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |