Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457795 | 0.92 | TTK (0.81) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL470040 | 0.91 | TTK (0.69) | TTKCYP3A4CYP2C9CYP2C19PIM1 | |
| SCHEMBL470035 | 0.90 | TTK (0.55) | TTKPIM1KCNH2 | |
| SCHEMBL10279709 | 0.89 | TTK (0.54) | TTKPIM1KCNH2 | |
| SCHEMBL10279711 | 0.89 | TTK (0.60) | TTKPIM1KCNH2 | |
| SCHEMBL457796 | 0.86 | TTK (0.81) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL470037 | 0.86 | TTK (0.61) | TTKPIM1KCNH2 | |
| SCHEMBL15556070 | 0.84 | TTK (0.82) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL457024 | 0.83 | TTK (0.83) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10279263 | 0.83 | TTK (0.51) | TTKPIM1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |