Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 13/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700267 | 1.00 | ACKR3 (0.47) | ACKR3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4700612 | 0.93 | ACKR3 (0.48) | ACKR3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4698476 | 0.81 | ACKR3 (0.38) | ACKR3 | |
| SCHEMBL5576818 | 0.80 | ACKR3 (0.57) | ACKR3L3MBTL1KDM4EHTT | |
| SCHEMBL14601239 | 0.80 | ACKR3 (0.57) | ACKR3L3MBTL1KDM4EHTT | |
| SCHEMBL3534544 | 0.78 | ACKR3 (0.54) | ACKR3 | |
| SCHEMBL4699928 | 0.78 | ACKR3 (0.51) | ACKR3TSHR | |
| SCHEMBL4699931 | 0.78 | ACKR3 (0.51) | ACKR3TSHR | |
| SCHEMBL4699933 | 0.78 | ACKR3 (0.51) | ACKR3TSHR | |
| SCHEMBL4755000 | 0.78 | ACKR3 (0.51) | ACKR3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909575-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | ChemoCentryx Inc (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002842-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |