Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700703 | 1.00 | PLG (0.44) | PLGPLATLMNAALDH1A1F2 | |
| Hydrochloric Acid SCHEMBL9390965 | 0.98 | PLG (0.43) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL688602 | 0.87 | PLG (0.53) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL5789042 | 0.87 | PLG (0.53) | PLGPLATLMNAALDH1A1F2 | |
| Hydrochloric Acid SCHEMBL1068668 | 0.85 | PLG (0.52) | PLGPLATLMNAALDH1A1F2 | |
| Hydrochloric Acid SCHEMBL11075182 | 0.85 | PLG (0.52) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL11179699 | 0.82 | PLG (0.48) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL5003662 | 0.81 | PLG (0.47) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL5003658 | 0.81 | PLG (0.47) | PLGPLATLMNAALDH1A1F2 | |
| SCHEMBL11185218 | 0.79 | PLG (0.46) | PLGPLATLMNAALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028234-A1 | USES OF ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID | XENOPORT, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |