Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26133008 | 0.98 | POLB (0.81) | POLBEPHX1L3MBTL1TSHRMAPT | |
| SCHEMBL6378905 | 0.98 | POLB (0.81) | POLBEPHX1L3MBTL1TSHRMAPT | |
| SCHEMBL24323730 | 0.98 | POLB (0.81) | POLBEPHX1L3MBTL1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4711713 | 0.96 | POLB (0.78) | POLBEPHX1L3MBTL1TSHRMAPT | |
| SCHEMBL1437818 | 0.92 | POLB (0.77) | POLBEPHX1L3MBTL1TSHRMAPT | |
| SCHEMBL10080421 | 0.91 | POLB (0.91) | POLBEPHX1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL7512372 | 0.91 | POLB (1.00) | POLBEPHX1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL1972336 | 0.90 | POLB (0.74) | POLBEPHX1L3MBTL1MAPTHTT | |
| SCHEMBL3274450 | 0.90 | POLB (0.74) | POLBEPHX1L3MBTL1MAPTHTT | |
| Hydrochloric Acid SCHEMBL30473852 | 0.89 | POLB (0.88) | POLBEPHX1L3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814828-B9 | PERIPHERALLY RESTRICTED DIPHENYL PURINE DERIVATIVES | RES TRIANGLE INST (US) | 2020-10-07 | — | — | EP | disclosed |
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | disclosed |