Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673547 | 0.88 | HTT (0.53) | MAPTKMT2AALDH1A1TDP1HTT | |
| Hydrochloric Acid SCHEMBL915077 | 0.87 | HTT (0.52) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL7747067 | 0.84 | HTT (0.54) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL7747069 | 0.84 | HTT (0.54) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL4698002 | 0.84 | HTT (0.54) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL4699409 | 0.83 | KMT2A (0.51) | MAPTKMT2AALDH1A1TDP1HTT | |
| Acetic Acid SCHEMBL914888 | 0.81 | KMT2A (0.51) | MAPTKMT2AALDH1A1TDP1HTT | |
| Acetic Acid SCHEMBL914887 | 0.81 | KMT2A (0.51) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL4701658 | 0.80 | KMT2A (0.54) | MAPTKMT2AALDH1A1TDP1HTT | |
| SCHEMBL4701661 | 0.80 | KMT2A (0.54) | MAPTKMT2AALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |