Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 17/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470190 | 0.89 | TTK (0.48) | FYNTTKPOLB | |
| SCHEMBL470013 | 0.88 | CYP1A2 (0.54) | FYNTTKPOLB | |
| SCHEMBL10279098 | 0.81 | FYN (0.46) | FYNPOLBERN1 | |
| SCHEMBL10279180 | 0.81 | TTK (0.56) | FYNTTKERN1 | |
| SCHEMBL10279097 | 0.79 | TTK (0.51) | TTKERN1 | |
| SCHEMBL10279096 | 0.78 | FYN (0.41) | FYNTTKERN1 | |
| SCHEMBL470001 | 0.78 | KCNN1 (0.44) | FYNPOLB | |
| SCHEMBL2692922 | 0.75 | CISD1 (0.54) | POLB | |
| SCHEMBL462792 | 0.73 | ERN1 (0.43) | FYNTTKERN1 | |
| SCHEMBL10279181 | 0.70 | TTK (0.59) | FYNTTKERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014020041-A1 | COMBINATIONS FOR THE TREATMENT OF CANCER | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-02-06 | — | — | WO | claimed |
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |