Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775134 | 1.00 | PARP14 (0.37) | PARP14HRH3TLR7CYP3A4DYRK1A | |
| SCHEMBL1774906 | 0.94 | CYP3A4 (0.37) | HRH3CYP3A4SRCABL1GRM5 | |
| SCHEMBL1774146 | 0.89 | PARP14 (0.39) | PARP14TLR7CYP3A4DYRK1AGRM5 | |
| SCHEMBL1775116 | 0.85 | TLR7 (0.36) | PARP14TLR7CYP3A4DYRK1AGRM5 | |
| SCHEMBL1774744 | 0.83 | TLR7 (0.45) | TLR7 | |
| SCHEMBL10237183 | 0.83 | TLR7 (0.45) | TLR7 | |
| SCHEMBL1775756 | 0.82 | MEN1 (0.41) | SRCNPC1 | |
| SCHEMBL1773836 | 0.82 | CYP3A4 (0.39) | TLR7CYP3A4GRM5NPC1RAB9A | |
| SCHEMBL10237173 | 0.82 | CYP3A4 (0.39) | TLR7CYP3A4GRM5NPC1RAB9A | |
| SCHEMBL1773415 | 0.81 | TLR7 (0.44) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831226-A4 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831226-A2 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006074003-A2 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |