⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700985 | 0.85 | — | — | |
| SCHEMBL4703838 | 0.62 | — | — | |
| SCHEMBL219352 | 0.62 | — | — | |
| SCHEMBL6737899 | 0.62 | — | — | |
| SCHEMBL17581084 | 0.60 | — | — | |
| SCHEMBL15647356 | 0.57 | CA1 (0.42) | — | |
| SCHEMBL7775509 | 0.55 | — | — | |
| SCHEMBL165797 | 0.53 | — | — | |
| SCHEMBL21810826 | 0.52 | — | — | |
| SCHEMBL6970551 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559714-B1 | Process for the preparation of 2-alkyl-3-aminothiophene derivatives and 3-aminothiophene derivatives | MITSUI CHEMICALS INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-7196207-B2 | Method for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS, INC. (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1036793-B1 | A process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative | MITSUI CHEMICALS INC (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-20050176971-A1 | Method for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS, INC. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1559714-A1 | Process for the preparation of 2-alkyl-3-aminothiophene derivatives and 3-aminothiophene derivatives | MITSUI CHEMICALS, INC. (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1524271-A1 | PROCESS FOR PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | Mitsui Chemicals, Inc. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-6331639-B2 | BY REACTING A 3-((ALKYL, ALKOXY, PHENYL OR HETEROARYL)CARBONYLAMINO)THIOPHENE WITH A KETONE IN THE PRESENCE OF AN ACID AND REDUCING THE REACTION MIXTURE; AGRICULTURAL FUNGICIDES | MITSUI CHEMICALS, INC. (JP) | 2001-12-18 | — | — | US | disclosed |
| US-6331634-B1 | FUNGICIDES | MITSUI CHEMICALS, INC. (JP) | 2001-12-18 | — | — | US | disclosed |
| US-20010023295-A1 | Process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative | KATSUTA HIROYUKI (JP) | 2001-09-20 | — | — | US | disclosed |
| US-6239282-B1 | ALKYLATING THE CORRESPONDING 3-AMIDOTHIOPHENE COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-1036793-A2 | A process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative | Mitsui Chemicals, Inc. (JP) | 2000-09-20 | — | — | EP | disclosed |