Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647957 | 1.00 | DPP4 (0.52) | DPP4DPP9DPP7DPP8 | |
| SCHEMBL647959 | 0.76 | DPP4 (0.53) | DPP4DPP9 | |
| SCHEMBL648398 | 0.76 | DPP4 (0.50) | DPP4DPP9 | |
| SCHEMBL646521 | 0.75 | DPP4 (0.61) | DPP4 | |
| SCHEMBL646728 | 0.72 | DPP4 (0.59) | DPP4DPP9DPP7DPP8 | |
| SCHEMBL647213 | 0.71 | DPP4 (0.68) | DPP4DPP9DPP8 | |
| SCHEMBL646369 | 0.71 | DPP4 (0.89) | DPP4DPP9DPP8 | |
| SCHEMBL1380732 | 0.71 | DPP4 (0.89) | DPP4DPP9DPP8 | |
| SCHEMBL645964 | 0.70 | DPP4 (0.68) | DPP4 | |
| SCHEMBL4983693 | 0.70 | DPP4 (0.60) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-B9 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1560811-B1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2007-08-01 | — | — | EP | disclosed |