Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.46 |
| ▸ | FYN | P06241 | 5/20 | 0.40 |
| ▸ | GRK5 | P34947 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469957 | 0.88 | TTK (0.55) | TTK | |
| SCHEMBL455986 | 0.86 | TTK (0.61) | TTK | |
| SCHEMBL469970 | 0.83 | TTK (0.50) | TTK | |
| SCHEMBL17416352 | 0.82 | TTK (0.59) | TTK | |
| SCHEMBL17416409 | 0.80 | TTK (0.60) | TTK | |
| SCHEMBL470316 | 0.80 | TTK (0.56) | TTK | |
| SCHEMBL456015 | 0.79 | TTK (0.71) | TTK | |
| SCHEMBL470171 | 0.77 | TTK (0.60) | TTKFYN | |
| SCHEMBL469904 | 0.77 | TTK (0.55) | TTK | |
| SCHEMBL10279109 | 0.76 | TTK (0.34) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |