Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697010 | 0.93 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5579132 | 0.90 | BACE1 (0.85) | BACE1CTSD | |
| SCHEMBL5579036 | 0.85 | BACE1 (0.66) | BACE1CTSD | |
| SCHEMBL5579034 | 0.84 | BACE1 (0.72) | BACE1CTSD | |
| SCHEMBL5579147 | 0.81 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL5579143 | 0.81 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL4702461 | 0.79 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL6701309 | 0.78 | BACE1 (0.68) | BACE1CTSD | |
| SCHEMBL6701304 | 0.78 | BACE1 (0.68) | BACE1CTSD | |
| SCHEMBL6699533 | 0.78 | BACE1 (0.77) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937638-A1 | METHODS OF TREATING AMYLOIDOSIS USING ARYL-CYCLOPROPYL DERIVATIVE ASPARTYL PROTEASE INHIBITORS | Elan Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047306-A1 | METHODS OF TREATING AMYLOIDOSIS USING ARYL-CYCLOPROPYL DERIVATIVE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |