Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69564 | 1.00 | ACE (0.43) | ACERENKDM4EF2LMNA | |
| SCHEMBL4703297 | 1.00 | ACE (0.43) | ACERENKDM4EF2LMNA | |
| SCHEMBL3403871 | 0.89 | ACE (0.37) | ACERENKDM4EF2LMNA | |
| SCHEMBL3403874 | 0.89 | ACE (0.37) | ACERENKDM4EF2LMNA | |
| SCHEMBL27698951 | 0.89 | ACE (0.37) | ACERENKDM4EF2LMNA | |
| SCHEMBL5320346 | 0.86 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| SCHEMBL21509266 | 0.81 | POLB (0.41) | ACERENKDM4EF2LMNA | |
| SCHEMBL21509268 | 0.81 | POLB (0.41) | ACERENKDM4EF2LMNA | |
| SCHEMBL1449915 | 0.81 | CYP1A2 (0.42) | LTA4HRAB9AALDH1A1 | |
| SCHEMBL13991699 | 0.80 | ATM (0.36) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331890-B1 | PROTECTED ORGANOBORONIC ACIDS WITH TUNABLE REACTIVITY, AND METHODS OF USE THEREOF | UNIV ILLINOIS (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2017027435-A1 | PROTECTED ORGANOBORONIC ACIDS WITH TUNABLE REACTIVITY, AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-02-16 | — | — | WO | disclosed |
| EP-1963323-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007065892-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2007-06-14 | — | — | WO | disclosed |