Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 6/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458279 | 0.80 | PIK3CD (0.70) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL457161 | 0.80 | PIK3CD (0.49) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL10280668 | 0.73 | PIK3CD (0.39) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL457116 | 0.71 | PIK3CD (0.56) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL456973 | 0.70 | PIK3CD (0.70) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL1778778 | 0.69 | PIK3CD (0.69) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL1250243 | 0.69 | PIK3CD (0.74) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL1251763 | 0.69 | PIK3CD (0.74) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL457583 | 0.69 | PIK3CD (0.74) | PIK3CDGSK3BPIK3CBPIM1PIK3CG | |
| SCHEMBL1779812 | 0.68 | PIK3CD (0.51) | PIK3CDGSK3BPIK3CBPIM1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |